DISAJP NEWS Vol. 42 September 4th, 2021

Dementia Improved Support Association of Japan

This email is sent to those who subscribe DISA NEWS, the newsletter from the Dementia Improved Support Association of Japan.

We deliver the newsletter on the 4th of each month to bring you valuable information, aiming to achieve the dementia-free world.


〇 Olympic / Paralympic Games and COVID-19 infection prevention
〇 RUTIN G – C PLUS, 360 tablets
〇 Latest news on dementia and its prevention
〇 100 things by Dr. Hasegawa, the developer of HDS-R
〇 Note on KOUKA

〇 Olympic / Paralympic Games and COVID-19 infection prevention

On July 23, 2021, Tokyo had the opening ceremony of the Olympic Games.
Narita International Airport saw the largest number of foreign arrivals from July 17th to 19th.
The Games, which had already started on 21th before the opening ceremony, finally closed on August 8.
It will be followed by the Paralympic Games held in August 24 to September 5.

The following is what National Institute of Infectious Diseases published on August 20
as the current situation of COVID-19 occurrence associated with the Olympic Games.

The analysis and report was performed by four organizations:

– National Institute of Infectious Diseases (NIID)
– Research Center for Crisis Management on Infectious Diseases
– Center for Field Epidemic Intelligence, Research and Professional Development (CFEIR)
– Infectious Diseases Surveillance Center

Surveillance period: July 1 to August 8, 2021 (tallied on August 9)

The data is based on information about COVID-19 cases associated with the Olympic Games
that was input into Health Center Real-time Information-sharing System on COVID-19 (HER-SYS).
The data gathering and analysis are targeted to athletes and related people, and game officials.
Published on August 20, 2021.


There were 453 cases of COVID-19 in total.
Athletes and related people accounted for 80 cases (18%), while game officials made up 373 cases (82%).
By domicile, foreign visitors covered 147 cases (32%), while domestic residents accounted for 306 cases (68%).

The number of the cases of athletes and related people increased from July 14 to its peak recorded on 22.
95% (76 in 80 cases) of them were foreign visitors’, while the domestic residents’ were only 5 % (4 cases).
93% of the former (71 in 76) was diagnosed within 14 days from the date of quarantine or entry,
and the remaining 7% (5) was done on the 15th day or later.
There were no case of domestic athletes reported.

On the other hand, the game officials, of which 81% (302 out of 373) is domestic residents and only 19% (71) is foreign visitors,
showed gradual increase from July 1.
There were no fetal case reported.


The number of the cases of athletes and related people became highest after 3 to 5 days from the entrance peaked.

Throughout the country, the number of infections began to increase dramatically from the Olympic Games.
This was a well expected conclusion, because infection control or awareness differed a lot from country to country.
Japan’s government and politicians clearly put economic elements ahead of the people’s safety.

We want to stress that we need to use our own head to decide what to do to protect our own lives.

A team in the Center for iPS Cell Research and Application at the Kyoto University conducted research on elderly and young people’s immune functions against COVID-19.
The result showed that the number of specific immune cells responsible for attacking virus was lower in elder people’s cases, which potentially led to their aggravation.

As for the Paralympic games, over 100 infections were found in the game officials before the opening.
Although about 90% of those who stays at the athlete’s village was vaccinated,
some should bear risks for aggravation, such as pre-existing diseases or problems on respiratory functions.
Vaccination works less effectively when immune is declined by an underlying diseases or drugs.
Experts agree that more strict infection control is needed among all the people concerned including caregivers.

The same goes for elderly people living with dementia, and their families and caregivers.

Please make sure that we need to keep infection prevention as follows after vaccination:

– Gargling and hand washing

– Wearing a mask

– Avoid having a meal with someone else

– Frequent ventilation

– Avoid meeting someone you haven’ t seen for a while

〇 RUTIN G – C PLUS, 360 tablets

RUTIN G – C PLUS provides the best balance of reishi and rutin.



Name: Processed Food of Reishi
Amount: 97.2g (270mg×360 tablets)
Dosage: Take 6 tablets with cold or lukewarm water for two times a day.
Ingredients: Maltitol, Vitamin C, Reishi Extract, Crystalline Cellulose,
Sucrose Fatty Acid Ester, Melia Azadirachta Leaf Extract, Charred Reishi Powder, Shellac
Price: 80,000JPY

Rutin is a kind of polyphenols typically contained in buckwheat, fig and many other plants.

It is known to strengthen blood vessels, as well as providing antioxidant actions, by affecting regulatory functions of capillaries and vessel walls.
Rutin is used in a variety of fields.
It goes very well with vitamin C by enhancing its absorption.
Blend with collagen also works a lot.
Being one of vitamin-like substances soluble in water,
rutin is called “vitamin P” along with hesperidin and some other substances.

The specific kind of rutin used for producing RUTIN G – C PLUS has antiviral effect.
Among all kinds of rutin contained in 200 or more plants, only a minority has the effect.
RUTIN G – C PLUS contains substances derived from one of those minor types.

Healthful effects of rutin:

– Prevention of bleeding disorders

– Prevention and symptom relief of lifestyle-related diseases

– Prevention of cardiac disorders

– Prevention of diabetes

– Prevention of dementia

– Symptom relief of osteoarthrosis

– Prevention of spots, wrinkles or sag of skin by enhancing vitamin C absorption

– Reinforcement of capillaries

What is more, rutin prevents bacteria invasion.

In Japan, a boy infected with COVID-19 recovered without sequelae,
with his fever gone down three days after taking RUTIN G.

Actually, the plants containing rutin have been used as crude drugs to control inflammation or bleeding, as well as to ease lower back pain.

Rutin was discovered in 1930’s.

It is called vitamin P for its positive effects in treating purpula, a disease causing bleeding under the skin or mucous membrane.
“P” came from “permeability”.
Now, vitamin P is considered to include hesperidin, quercetin and other substances beyond rutin.

Recent research showed that rutin also lowered blood pressure or blood glucose level, as well as activating pancreatic functions.

Oral administration of 25mg/kg of rutin to mice with cognitive deficits showed significant effects on a lipid peroxide TBARS, ADP Ribosyl polymerase, nitric oxide level, glutathione, glutathione peroxidase, glutathione reductase.

The results indicate that rutin attenuated inflammation by reducing the expression of cyclooxygenase-2 (COX-2), interleukin-8 (IL-8) and other substances, which suggests the substance’s effectiveness in preventing cognitive deficits.


Oral administration of 25mg/kg of rutin to mice with Parkinson’s disease for 3 weeks showed significant effects on motor functions
and dopamine receptors as well as cranial nerve-protective effects, which suggest that rutin prevents cranial nerve diseases.


〇 Latest news on dementia and its prevention

– Does chronic pain raise the risk of dementia, Alzheimer’s, or stroke?
Linking pain and dementia, stroke risk


– Do some diabetes drugs reduce the risk of Alzheimer’s?
Study finds people taking the drugs have fewer biomarkers, slower cognitive decline


– A study identified 15 novel biomarkers for diseases predisposing to dementia


– Seeking Early Signals of Dementia in Driving and Credit Scores
The pathologies underlying brain decline can begin years before symptoms emerge. Can everyday behavior provide warning?


– Propolis, Bee Honey, and Their Components Protect against Coronavirus Disease 2019 (COVID-19): A Review of In Silico, In Vitro, and Clinical Studies


〇 100 things by Dr. Hasegawa, the developer of HDS-R

At home and abroad, Dr. Kazuo Hasegawa, now 92, has enormously contributed to establishment of the groundwork for diagnosis of dementia.
In 2017, at the age of 88, he disclosed his disease.
After spending many years studying dementia, Dr. Hasegawa himself finally developed the disease.
He decided to make it public, because he wanted to let people know that anybody can have dementia.
And also, he wanted to make society more open to the disease.

Hoping to make it easier for those living with dementia to talk about the disease openly, he published a book titled I’m Enjoying my Spiritual Life with Dementia.

In the book Dr. Hasegawa shares 100 things he found.

51. People living with mild or moderate dementia still have the ability to think. Even those with severe cases can build emotional connections to others.
By being watched over fondly with much love, most of them hardly shows BPSD.

52. Although rehabilitation of those with dementia is supposed to be practiced based on their own will, supportive awareness and willingness of others are very important.
Forceful rehab will be pain and potentially lead to exacerbation of BPSD.

53. Caregiving for those with dementia goes on for almost eight years on average after their symptoms are noticed by others.

54. You have to admit that you can’t care for someone with dementia all by yourself.
Avoid making an assumption, such as calling for help is bothersome or you are on the absolutely right way.

55. Keep psychological distance.
That’s the caregiving with emotional leeway.

56. Revised Hasegawa’s Dementia Scale (HDS-R) is a simple cognitive test to provide information for diagnosis of dementia.
Since the first appearance as Hasegawa’s Dementia Scale (HDS) in 1974, it has been used at many medical facilities across the country.
I believe this scale help us draw out certain information from those living with dementia.
By serving as a detective unit to determine what kind of cognitive impairment is shown,
the scale’s nine questions contributes to the quality of life of those living with dementia.

57. In 1968, I started to tally the number of those with dementia symptoms in nursing homes and other facilities.
At that time, my mentor Dr. Naotake Shinfuku said to me, “Todays diagnosis must be consistent with the yesterday’s. You need to build the criteria.”
These words made me decide to develop the scale.
The scale had to be simple and accessible for anybody who wants to determine if one had dementia.
We managed to develop it, without a good reference in the world.

58. In developing the scale, I tried to make questions that every elderly person
with declined cognitive functions can answer in a short time, which are very easy for those
with normal cognitive functions but hard for those with dementia.

59. You can’t make a diagnosis only with this scale, because it is an auxiliary method of examination.
The score depends a lot on the questionee’s educational background or energy of the day.
Doctors need to make comprehensive decision, hearing from family members or other people who are close to the questionee.

60. It may be often forgotten,
but the first thing needed to care for those with dementia is good preparation of caregiver’s mind.

〇 Note on KOUKA

KOUKA is a processed food of Ganoderma lucidum.

The ingredients are edible linseed oil, extract essence from Ganoderma lucidum,
beer yeast (containing selenium), mackerel peptide DHA, EPA, fungus carbon powder (enzymatic decomposition product),
dextrin (encapsulant), gelatin, glycerin, glycerol ester of fatty acid, and pullulan.

KOUKA is chemical free food. It is designed to deliver reishi essence
and other substances that positively effect on cognitive functions to the brain through the blood-brain barrier.
By improving microcirculation, it enhances oxygen and nutrition supply to the brain,
as well as excretion of waste products from the brain.

Japan Post announced to resume the operation of EMS to US,
having been suspended due to spread of COVID-19, in June with increased charge.
The operation is already back in service to Europe and Asia.
Every overseas order for one package costs the total amount of 42,000JPY
including the product’s price (39,000JPY) and EMS charge (3,000JPY).
We accept PayPal payment.
Don’t forget to check on the custom duty for your country before ordering.
The custom duty, if any, will be charged to the recipient.


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