DISAJP NEWS ☆ vol.5, August 4th, 2018 – early-onset dementia –
We, at general incorporated association, Dementia Improved support Association of Japan tackles to make dementia zero for dementia patients and their families in Japan as well as in the world. We deliver E-mail Newsletter on 4th in every month.
Today, We’d like to talk to you about the contents
1. Professor Masao Mori received patent for invention for constituent for cognitive functional
2. The tendency of increasing early-onset dementia
3. The difficulties of diagnosis of dementia
4. Alzheimer’s starts 25 years before the onset.
5. Check list of dementia by American Alzheimer’s Association
6. Approach to collect evidence
7. Alzheimer’s dementia will take the following stages.
8. Kouka, made with exceptionally high quality reishi
1. Professor Masao Mori received patent for invention for constituent for cognitive functional
Professor Masao Mori who developed KOUKA that Dementia Improved support Association of Japan recommends and researcher of rare physiology ( microcirculation ) in Japan, professor advisor at Shanghai Medical Institute in Fudan University ( ex Shanghai Medical University visiting professor in pharmacognosy ), director in microcirculation institute, academic advisor of Japanese and Chinese crude drug research institute, received patent for invention for constituent for cognitive functional disorder improvement.
2. The tendency of increasing early-onset dementia
Speaking of dementia, it has the image of elderly people. But early-onset dementia which outbreaks under sixty-five years old has been increasing.
Many of the young people’s dementia are Alzheimer’s disease and many outbreaks are from late forties to early sixties. The occasion of doubtful of dementia is not forgefulness which happens in elderly people but the failures of works or strange psychological conditions and surrounding people will recognize that. Because prime of one’s working life, it is often mistaken as fatigue out of work, depression symptom or menopausal disturbance etc, That leads to be delayed the diagnosis and that is one of the features of early-onset dementia. It happens more men than women and the average onset age is fifty-one years old, the majority is cerebrovascular and Alzheimer’s types of dementia. There is also alcoholic dementia.
3. The difficulties of diagnosis of dementia
The judgement of dementia differs by person among nursing care profession and the same is true for doctors. There are cases that it was not dementia even though a doctor diagnosed as dementia. It is difficult to diagnose accurately because the diagnosing standard is from the patients or their families even though diagnosed by specialist for dementia. Under this circumstance, it is required to set up common standard or inspections or methods of diagnosis that anyone can understand. Especially, the features of early-onset dementia are memory disorder or impaired orientation. In early-onset dementia, symptoms such as forgetfulness or forgetting the important plan on the job can be seen, but it is easily neglected because it is busy or they are tired just because their age are still young. The family members near them can recognize easily but they don’t want to admit that they are not old and it may take time to reach the diagnosis.
4. Alzheimer’s starts 25 years before the onset.
In American study, it was announced that the concentration of protein called amyloid beta in the cerebrospiral fluid starts to fall 25 years before diagnosed as Alzheimer’s and the deposition of amyloid beta in the brain and the atrophy of the brain are 15 years before onset and degeneration of the memory and brain metabolism starts 10 years before and general degeneration of the cognitive function starts 5 years before diagnosis.
5. Check list of dementia by American Alzheimer’s Association
At American Alzheimer’s Association, they put ten check list for dementia.
http://www.alz.org/national/documents/checklist_10signs.pdf
6. Approach to collect evidence
As above list, the mainstream diagnostic approach is interview, such as Japanese Hasegawa’s Dementia Scale or Mini-Mental State Examination (MMES) developed by Folstein et al. in the United States, 1975. These methods are not necessarily objective or scientific. Our association use Miculator, a microcirculation monitoring device, to observe blood vessels and determine the risk for dementia from blood flow state in cerebral vessels.
Hidekazu Tomimoto, a professor in Department of Neurology, Faculty of Medicine, Mie University, says amyloid beta precursor protein which differs from neuron appears in cerebrovascular endothelial cells, in his article titled “A Role of Cerebral Microvascular Disturbance in Dementia”.
https://www.jstage.jst.go.jp/article/jsnt/33/2/33_194/_pdf
We aim to combine our research with a diagnosis technique using 0.5cc of blood developed by Nobel Prize winner Koichi Tanaka from Shimadzu Corporation and his team, to collect evidence on treatment, prevention and amelioration of dementia in early stage.
7. Alzheimer’s dementia will take the following stages.
Like a baby increases things that he or she can do one by one, the dementia patient loses things that he or she can do. Like the babies have individual differences, the progress of dementia has individual differences and the progress of dementia vary by individual and it can be delayed by surrounding environments or involvements.
https://disajp.org/knowledge-en/1339/
8. Kouka, made with exceptionally high quality reishi
From a physiological perspective, we believe adopting Chinese medicine besides the Western is enormously beneficial to prevention of dementia.
Among others, the king of Kanpo reishi regulates immune function, activating the system when it’s weakened and easing it when it’s excessive.
Reishi is also effective on regulating blood sugar level, lowering high blood pressure, preventing formation of blood clots, ameliorating hyperlipidemia or hepatitis B and so on.
These kinds of disorders also accelerate progression of dementia.
Kouka was developed in Japan but overseas shipment is now available.
You can purchase Kouka at the following website. We accept overseas shipping from Japan.
(Shipping fee to Singapore, Taiwan or Hong Kong varies from JPY 2,000 to 3,000, so we are available for each consultation via e-mail. We accept credit card transaction via PayPal.)
Email: info@disajp.org
We will appreciate your feedback.
DISAJP NEWS（ E-Mail Newsletter）
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